Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28136124 | 0.86 | GFER (0.49) | HRH3MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL26123821 | 0.84 | HRH3 (0.47) | HRH3AKR1C3MAPTPOLBCYP2C9 | |
| SCHEMBL578125 | 0.84 | ALDH1A1 (0.46) | HRH3AKR1C3MAPTPOLBCYP2C9 | |
| SCHEMBL28379144 | 0.84 | POLB (0.52) | HRH3MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL28812232 | 0.84 | ATM (0.42) | AKR1C3MAPTUSP2KMT2AGPR119 | |
| SCHEMBL29182668 | 0.82 | NPY5R (0.43) | HRH3MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL16669518 | 0.81 | NPY5R (0.45) | HRH3AKR1C3MAPTPOLBCYP2C9 | |
| SCHEMBL23300904 | 0.80 | MAPT (0.69) | AKR1C3MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL21541871 | 0.80 | MAPT (0.69) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29105998 | 0.79 | HRH3 (0.38) | HRH3MAPTPOLBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453679-A | Targeted protein degradation | C4医药公司 | 2021-09-28 | — | — | CN | disclosed |