Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631027 | 0.84 | HRH3 (0.47) | AKR1C3USP2KMT2AMAPTL3MBTL1 | |
| SCHEMBL28598617 | 0.83 | NOTUM (0.45) | ATMUSP2KMT2ACYP1A2CYP2D6 | |
| SCHEMBL31084046 | 0.73 | HRH3 (0.37) | AKR1C3MAPT | |
| SCHEMBL22804834 | 0.72 | NOTUM (0.51) | AKR1C3USP2KMT2AMAPTRXFP1 | |
| SCHEMBL29117227 | 0.71 | NOTUM (0.55) | MAPTGPR119 | |
| SCHEMBL28817090 | 0.71 | KDM1A (0.37) | ATMAKR1C3PTPRFPTPN2PTPN1 | |
| SCHEMBL29117230 | 0.71 | NOTUM (0.55) | MAPTGPR119 | |
| SCHEMBL15224314 | 0.70 | HRH3 (0.52) | AKR1C3 | |
| SCHEMBL31465552 | 0.70 | KDM1A (0.40) | AKR1C3USP2KMT2AALOX15MAPK1 | |
| SCHEMBL20640028 | 0.70 | MAPT (0.50) | AKR1C3USP2KMT2AMAPTCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929345-A | Substituted pyrazole compounds as TOLL receptor inhibitors | 百时美施贵宝公司 | 2022-08-19 | — | — | CN | disclosed |