Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nudol SCHEMBL3971615 | 0.80 | TUBB4A (0.54) | ESR1ESR2ABL1KDM4EGAA | |
| SCHEMBL5804555 | 0.79 | TUBB4A (0.64) | ESR1ESR2ABL1KDM4EGAA | |
| SCHEMBL27939366 | 0.78 | MAPT (0.52) | ESR1ESR2ABL1KDM4EGAA | |
| SCHEMBL9623607 | 0.75 | ESR1 (0.75) | ESR1ESR2ABL1KDM4EGAA | |
| SCHEMBL28245550 | 0.73 | MAPT (0.51) | ESR1ESR2ABL1KDM4EGAA | |
| Flavanthrinin SCHEMBL29054933 | 0.72 | ESR1 (0.51) | ESR1ESR2ABL1KDM4EGAA | |
| Flavanthrinin SCHEMBL30544847 | 0.72 | ESR1 (0.51) | ESR1ESR2ABL1KDM4EGAA | |
| Flavanthrinin SCHEMBL30544846 | 0.72 | ESR1 (0.51) | ESR1ESR2ABL1KDM4EGAA | |
| SCHEMBL3807213 | 0.72 | KDM4E (0.40) | ESR1ESR2KDM4EGAAPOLB | |
| SCHEMBL19612320 | 0.72 | ESR1 (0.50) | ESR1ESR2ABL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113403362-A | Method for detecting effect of 1,5, 6-trimethoxy-2, 7-dihydroxyphenanthrene on HepG-2 cells and application | 沈阳药科大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-113384564-A | Application of p53 target-based trimethoxy dihydroxy phenanthrene compound in cervical cancer resistance and detection method | 沈阳药科大学 | 2021-09-14 | — | — | CN | disclosed |