Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804555 | 0.85 | TUBB4A (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29770963 | 0.81 | ESR1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5804536 | 0.81 | ESR1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27939366 | 0.81 | MAPT (0.52) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28632540 | 0.80 | ESR1 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9623607 | 0.79 | ESR1 (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11508300 | 0.79 | MCL1 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29409811 | 0.78 | ABL1 (0.53) | ESR1ESR2ABL1KDM4EGAA | |
| SCHEMBL22657846 | 0.78 | ABL1 (0.53) | ESR1ESR2ABL1KDM4EGAA | |
| SCHEMBL29409808 | 0.78 | ABL1 (0.53) | ESR1ESR2ABL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | claimed |
| WO-2009047791-A2 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-04-16 | — | — | WO | claimed |
| CN-108497548-A | A kind of stem of noble dendrobium medicinal extract and its application in cigarette | 河南中烟工业有限责任公司 | 2018-09-07 | — | — | CN | disclosed |
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | disclosed |
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | disclosed |
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | disclosed |
| WO-2009047791-A2 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009047791-A2 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | TLR4, TLR5, TLR1 | TUBB4A 2543/4885TUBB 2809/4885TUBA3C 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.