Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.75 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.75 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493121 | 0.86 | ESR1 (0.62) | ESR1ESR2MAOBABL1ABCB1 | |
| SCHEMBL2187208 | 0.86 | ESR1 (0.62) | ESR1ESR2MAOBABL1ABCB1 | |
| SCHEMBL5980579 | 0.86 | ESR2 (1.00) | ESR1ESR2ABL1ABCB1BCR | |
| Nudol SCHEMBL3971615 | 0.79 | TUBB4A (0.54) | ESR1ESR2MAOBABL1ABCB1 | |
| SCHEMBL9623295 | 0.79 | ESR1 (0.55) | ESR1ESR2MAOBCDK2TDP1 | |
| SCHEMBL1434455 | 0.78 | ESR1 (0.56) | ESR1ESR2CA12CA1CA7 | |
| SCHEMBL4357384 | 0.78 | ESR1 (0.56) | ESR1ESR2TDP1CA12CA1 | |
| SCHEMBL4138140 | 0.78 | ESR1 (0.49) | ESR1ESR2AURKACDK1CDK4 | |
| SCHEMBL10764502 | 0.77 | ESR2 (0.47) | ESR1ESR2POLBTLR8MEN1 | |
| SCHEMBL28741358 | 0.76 | ESR1 (0.48) | ESR1ESR2ABL1ABCB1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398052-A2 | Low-viscosity polyarylene sulfide mouldings | BAYER AG (DE) | 1990-11-22 | — | — | EP | claimed |
| EP-0212944-B1 | MELT-PROCESSABLE AROMATIC COPOLYESTER | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4746721-A | ENGINEERING PLASTICS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1988-05-24 | — | — | US | disclosed |