SCHEMBL2863255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2868379	0.91	TTK (0.47)	TTKNTRK1ADORA3ADORA2AADORA2B
	SCHEMBL2867285	0.84	ITK (0.45)	TTKMAPK8GSK3BITK
	SCHEMBL2864323	0.81	MAP2K4 (0.51)	NTRK1MAP2K4MAP2K7
	SCHEMBL2863645	0.79	TTK (0.56)	TTKMAPTSMN1; SMN2
	SCHEMBL4345565	0.78	MAPK10 (0.47)	ADORA3ADORA2AADORA2BADORA1MAPK8
	SCHEMBL4341168	0.78	HPGDS (0.44)	MAP2K4MAP2K7SMN1; SMN2GSK3AGSK3B
	SCHEMBL4343139	0.78	POLB (0.49)	ADORA3ADORA2AADORA1MAPTSMN1; SMN2
	SCHEMBL2868575	0.78	POLB (0.45)	TTKPLK4SMN1; SMN2
	SCHEMBL4341030	0.78	HPGDS (0.44)	MAP2K4MAP2K7SMN1; SMN2GSK3AGSK3B
	SCHEMBL2861586	0.78	MAP2K4 (0.56)	MAP2K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.