SCHEMBL28632562

SCHEMBL28632562

CCC(O)c1c(C#N)cc(I)c(O)c1I

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.42
ALB P02768 1/20 0.42
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10695025 0.69 TTR (0.48) TTRALB
SCHEMBL28632561 0.64 TTR (0.39) TTRALBTDP1
SCHEMBL10763743 0.64 TDP1 (0.40) TTRALBTDP1
SCHEMBL22991560 0.63 TTR (0.42) TTRALBTDP1
SCHEMBL27185441 0.61 TTR (0.48) TTRALB
SCHEMBL6089702 0.61 TSHR (0.38) TDP1
Ioxynil SCHEMBL1701373 0.61 TTR (1.00) TTRALB
Ioxynil SCHEMBL39616 0.61 TTR (1.00) TTRALB
SCHEMBL10495691 0.60 TTR (0.52) TTRALBTDP1
SCHEMBL7929990 0.60 TTR (0.44) TTRALBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997838-B Silicone-polyether copolymers, sealants including silicone-polyether copolymers, and related methods 美国陶氏有机硅公司 2021-10-01 CN disclosed
CN-110997839-B Silicone-polyether copolymer, method of preparing silicone-polyether copolymer, and sealant including silicone-polyether copolymer 美国陶氏有机硅公司 2021-09-14 CN disclosed
CN-110997840-B Silicone-polyether copolymers, isocyanate-functionalized silicone-polyether copolymers formed therewith, silicone-polyether-urethane copolymers, sealants including the same, and related methods 美国陶氏有机硅公司 2021-09-07 CN disclosed