Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aminosalicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.55 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminosalicylic Acid SCHEMBL28186850 | 0.84 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Salicylic Acid SCHEMBL3269577 | 0.82 | KDM4E (0.69) | ALDH1A1MAPTKDM4ECYP3A4TRIM24 | |
| Aminosalicylic Acid SCHEMBL30337954 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL29450213 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL3333393 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL2262 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL9437474 | 0.80 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL11788850 | 0.80 | ALDH1A1 (0.96) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL564092 | 0.80 | ALDH1A1 (0.96) | ALDH1A1MAPTKDM4ECYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL1047422 | 0.80 | ALDH1A1 (0.96) | ALDH1A1MAPTKDM4ECYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304986-A | Shell powder-based photocatalytic self-cleaning mildew-proof interior wall coating and preparation method thereof | 安徽中科思沃生物科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115304986-A | Shell powder-based photocatalytic self-cleaning mildew-proof interior wall coating and preparation method thereof | 安徽中科思沃生物科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-113461839-A | Preparation method of Schiff base rare earth catalyst and application of Schiff base rare earth catalyst in bacteriostatic polyacrylamide flocculant | 安徽天润化学工业股份有限公司 | 2021-10-01 | — | — | CN | disclosed |