SCHEMBL28632594

SCHEMBL28632594

N#CN1C=Cc2ccccc2C1.[H+]

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
HDAC3 O15379 1/20 0.35
PARP1 P09874 1/20 0.32
HSD17B3 P37058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1014977 0.98 CA1 (0.41) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL1389215 0.79 HDAC3 (0.38) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL28319871 0.74 SIGMAR1 (0.32)
SCHEMBL9400605 0.71 CA1 (0.38) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL28526384 0.71 HDAC3 (0.45) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL3069885 0.71 HDAC3 (0.43) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL27842483 0.71 HDAC3 (0.37) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL13932579 0.68 HDAC3 (0.38) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL1564351 0.68 HDAC3 (0.41) CA1CA2HDAC3PARP1HSD17B3
SCHEMBL11353696 0.68 HDAC3 (0.38) CA1CA2HDAC3PARP1HSD17B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113200912-B Method for synthesizing cyanamide 南昌大学 2022-12-06 CN disclosed
CN-113200912-A Method for synthesizing cyanamide 南昌大学 2021-08-03 CN disclosed