Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20928065 | 0.82 | TP53 (0.42) | TP53ALOX5PTGS2ALDH1A1 | |
| SCHEMBL657316 | 0.80 | TP53 (0.57) | TP53MGLLAKR1C3HDAC2ALOX5 | |
| SCHEMBL180460 | 0.79 | AKR1C3 (0.52) | AKR1C3ALDH1A1 | |
| SCHEMBL5439935 | 0.79 | AKR1C3 (0.45) | TRIM24TRIM33TP53MGLLAKR1C3 | |
| SCHEMBL3095394 | 0.79 | AKR1C3 (0.71) | TRIM24TRIM33TP53AKR1C3KMO | |
| SCHEMBL5158829 | 0.76 | MAOA (0.44) | TRIM24TRIM33TP53MGLLMAOA | |
| SCHEMBL2843934 | 0.75 | MAOA (0.48) | TRIM24TRIM33TP53MGLLMAOA | |
| SCHEMBL22202969 | 0.74 | ALDH1A1 (0.56) | AKR1C3MAOAALDH1A1 | |
| SCHEMBL3757538 | 0.74 | LCK (0.54) | MAOAALDH1A1 | |
| SCHEMBL27767060 | 0.73 | TRIM24 (0.40) | TRIM24TRIM33TP53MGLLMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134343-B | Method for alkenylating C-2 position of indole | 山东理工大学 | 2021-10-08 | — | — | CN | disclosed |