SCHEMBL28633433

SCHEMBL28633433

c1ccc2ncc(-c3ccc(Nc4ccc(-c5cnc6ccccc6c5)cc4)cc3)cc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 3/20 0.64
PDGFRA P16234 3/20 0.64
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA9 Q16790 1/20 0.58
PIK3CD O00329 2/20 0.57
PIK3CA P42336 2/20 0.57
CYP2A6 P11509 1/20 0.56
BIRC5 O15392 1/20 0.54
KDM1A O60341 1/20 0.51
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
PIK3CB P42338 1/20 0.49
MTOR P42345 1/20 0.49
PIK3CG P48736 1/20 0.49
TDP2 O95551 1/20 0.48
MAP4K4 O95819 1/20 0.48
CSNK1G2 P78368 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29449763 1.00 PDGFRB (0.64) PDGFRBPDGFRACA12CA1CA2
SCHEMBL483375 0.86 PDGFRB (0.60) PDGFRBPDGFRACA12CA1CA2
SCHEMBL29375510 0.85 PDGFRB (0.72) PDGFRBPDGFRACA12CA1CA2
SCHEMBL26829682 0.85 PDGFRB (0.72) PDGFRBPDGFRACA12CA1CA2
SCHEMBL24621829 0.85 PDGFRB (0.72) PDGFRBPDGFRACA12CA1CA2
SCHEMBL2772360 0.84 PDGFRB (0.77) PDGFRBPDGFRACA12CA1CA2
SCHEMBL32667946 0.84 PDGFRB (0.77) PDGFRBPDGFRACA12CA1CA2
SCHEMBL708999 0.83 PDGFRB (0.75) PDGFRBPDGFRACA12CA1CA2
SCHEMBL23384652 0.83 TDP2 (0.47) PDGFRBPDGFRACA12CA1CA2
SCHEMBL4155149 0.82 CYP2A6 (0.56) PDGFRBPDGFRACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115991668-A Novel compound for coating layer and organic light-emitting element comprising same 东进世美肯株式会社 2023-04-21 CN disclosed
CN-115991654-A Novel compound for coating layer and organic light-emitting element comprising same 东进世美肯株式会社 2023-04-21 CN disclosed
CN-115943142-A Novel compound for capping layer and organic light-emitting element including the same 东进世美肯株式会社 2023-04-07 CN disclosed
CN-114181146-A Novel compound for capping layer and organic light-emitting element including same 东进世美肯株式会社 2022-03-15 CN disclosed
CN-113527235-A Novel compound for cover layer and organic light-emitting element comprising same 东进世美肯株式会社 2021-10-22 CN disclosed
CN-113527232-A Novel compound for cover layer and organic light-emitting element comprising same 东进世美肯株式会社 2021-10-22 CN disclosed