SCHEMBL483375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29449763	0.86	PDGFRB (0.64)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL28633433	0.86	PDGFRB (0.64)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL24621829	0.82	PDGFRB (0.72)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL29375510	0.82	PDGFRB (0.72)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL26829682	0.82	PDGFRB (0.72)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL20759182	0.82	EGFR (0.53)	PDGFRBPDGFRACYP2A6BIRC5MAP4K4
	SCHEMBL32667946	0.82	PDGFRB (0.77)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL2772360	0.82	PDGFRB (0.77)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL8370258	0.81	PDGFRB (0.66)	PDGFRBPDGFRACA12CA1CA2
	SCHEMBL23555381	0.81	PDGFRB (0.66)	PDGFRBPDGFRACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.