SCHEMBL28633665

SCHEMBL28633665

Nc1ccc(-c2ccccc2-c2ccc(-c3ccc4ccccc4c3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.56
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 3/20 0.56
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
PRKCZ Q05513 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
PLAU P00749 1/20 0.49
GSTP1 P09211 1/20 0.48
TDP1 Q9NUW8 3/20 0.48
ALOX15 P16050 1/20 0.48
CASP1 P29466 1/20 0.48
CASP7 P55210 1/20 0.48
HBB P68871 1/20 0.48
HIF1A Q16665 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
CYP1A2 P05177 1/20 0.47
ALOX5 P09917 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29441264 0.92 CYP3A4 (0.65) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL28981808 0.92 CYP3A4 (0.65) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL28528867 0.92 CYP3A4 (0.65) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL6537114 0.92 CYP3A4 (0.65) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL27557165 0.87 CYP3A4 (0.55) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL24079285 0.87 ALDH1A1 (0.55) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL31302866 0.85 CYP3A4 (0.53) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL28635558 0.85 MAOA (0.57) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL24079323 0.85 CYP3A4 (0.53) CYP3A4ALDH1A1HSD17B10ESR1ESR2
SCHEMBL30127816 0.85 CYP3A4 (0.53) CYP3A4ALDH1A1HSD17B10ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493448-A Compound for organic photoelectric device, composition for organic photoelectric device, and display device 三星SDI株式会社 2021-10-12 CN disclosed