SCHEMBL28635558

SCHEMBL28635558

Nc1cccc(-c2ccccc2-c2ccc(-c3ccc4ccccc4c3)cc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.57
HSD17B1 P14061 2/20 0.49
HSD17B2 P37059 2/20 0.49
CYP3A4 P08684 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
GSTP1 P09211 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
MAPT P10636 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
DHFR P00374 1/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
CA12 O43570 1/20 0.45
MAP4K4 O95819 1/20 0.45
KDM4E B2RXH2 1/20 0.44
HDAC4 P56524 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL978013 0.89 MAOA (0.64) MAOAHSD17B1HSD17B2CYP3A4ALDH1A1
SCHEMBL30469312 0.89 MAOA (0.64) MAOAHSD17B1HSD17B2CYP3A4ALDH1A1
SCHEMBL29303802 0.87 MAOA (0.61) MAOAHSD17B1HSD17B2CYP3A4ALDH1A1
SCHEMBL28633665 0.85 CYP3A4 (0.56) HSD17B1HSD17B2CYP3A4ALDH1A1HSD17B10
SCHEMBL24079285 0.84 ALDH1A1 (0.55) HSD17B1HSD17B2CYP3A4ALDH1A1HSD17B10
SCHEMBL24079323 0.83 CYP3A4 (0.53) MAOAHSD17B1HSD17B2CYP3A4ALDH1A1
SCHEMBL31302866 0.83 CYP3A4 (0.53) MAOAHSD17B1HSD17B2CYP3A4ALDH1A1
SCHEMBL30127816 0.83 CYP3A4 (0.53) MAOAHSD17B1HSD17B2CYP3A4ALDH1A1
SCHEMBL27336143 0.81 MAOA (0.58) MAOACYP3A4ALDH1A1HSD17B10MAPT
SCHEMBL10492397 0.81 GSTP1 (0.61) HSD17B1HSD17B2ALDH1A1HSD17B10GSTP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113493448-A Compound for organic photoelectric device, composition for organic photoelectric device, and display device 三星SDI株式会社 2021-10-12 CN disclosed