Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.56 |
| ▸ | PLK4 | O00444 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.56 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | PAK4 | O96013 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28651984 | 0.82 | ALDH1A1 (0.64) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL28633762 | 0.82 | GAA (0.66) | RAB9AALDH1A1EPHX1GAAMAPT | |
| SCHEMBL28641155 | 0.82 | NOX1 (0.66) | NOX1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL28636321 | 0.81 | GAA (0.73) | NOX1NPC1RAB9AALDH1A1GAA | |
| SCHEMBL28636036 | 0.80 | NPC1 (0.68) | NPC1ALDH1A1GAAMAPTMEN1 | |
| SCHEMBL1002285 | 0.78 | NPC1 (0.61) | NPC1RAB9AALDH1A1EPHX1GAA | |
| SCHEMBL28924353 | 0.78 | EPHX2 (0.56) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL28640790 | 0.78 | GAA (0.61) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL5445907 | 0.78 | MAPT (0.75) | NOX1NPC1RAB9AALDH1A1EPHX1 | |
| SCHEMBL8956455 | 0.78 | MAPT (0.75) | NOX1NPC1RAB9AALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | claimed |
| CN-113480524-B | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | disclosed |