Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633748 | 0.82 | NOX1 (0.66) | GAAPKMMEN1KMT2ARAB9A | |
| SCHEMBL28641155 | 0.82 | NOX1 (0.66) | GAAPKMMEN1KMT2ARAB9A | |
| SCHEMBL28651984 | 0.82 | ALDH1A1 (0.64) | GAAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28636321 | 0.81 | GAA (0.73) | GAAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28641144 | 0.80 | ALDH1A1 (0.61) | GAAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL25132398 | 0.78 | GAA (0.60) | GAAPKMMEN1KMT2ARAB9A | |
| SCHEMBL28924353 | 0.78 | EPHX2 (0.56) | GAAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28640790 | 0.78 | GAA (0.61) | GAAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL5455602 | 0.78 | MAPT (0.83) | GAAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL8956372 | 0.78 | MAPT (0.83) | GAAMEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | claimed |
| CN-113480524-B | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | disclosed |