Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | RNF4 | P78317 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28923946 | 0.89 | ALDH1A1 (0.46) | BCL2A1MAPTKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL28645488 | 0.89 | MAPK1 (0.43) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28634158 | 0.89 | ALDH1A1 (0.41) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL20236541 | 0.88 | CA1 (0.47) | CA1CA2MEN1KMT2ABCL2A1 | |
| SCHEMBL28627937 | 0.88 | LMNA (0.43) | MEN1KMT2ABCL2A1MAPTKDM4E | |
| SCHEMBL28637466 | 0.87 | PTGES (0.43) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL28647144 | 0.87 | CA1 (0.46) | CA1CA2MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL20236710 | 0.87 | CA1 (0.46) | CA1CA2MEN1KMT2ABCL2A1 | |
| SCHEMBL17618071 | 0.87 | KMT2A (0.54) | MEN1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL20236160 | 0.87 | KDM4E (0.49) | CA1CA2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137518-B | 1,3, 4-oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2021-08-31 | — | — | CN | disclosed |