Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15650312 | 0.85 | ALDH1A1 (0.70) | TAAR1LTB4RLTB4R2ALDH1A1RAB9A | |
| SCHEMBL2062823 | 0.83 | RAB9A (0.69) | TAAR1LTB4RLTB4R2ALDH1A1RAB9A | |
| SCHEMBL2018753 | 0.77 | TAAR1 (0.55) | TAAR1LTB4RLTB4R2ALDH1A1KDM4E | |
| SCHEMBL16438514 | 0.75 | TAAR1 (0.58) | TAAR1LTB4RLTB4R2HTTSMN1; SMN2 | |
| SCHEMBL1129151 | 0.73 | TAAR1 (0.50) | TAAR1LTB4RLTB4R2ALDH1A1RAB9A | |
| SCHEMBL1239197 | 0.72 | TAAR1 (1.00) | TAAR1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL3139297 | 0.72 | TAAR1 (0.52) | TAAR1KMT2AMEN1POLBCTDSP1 | |
| SCHEMBL16435712 | 0.71 | KMT2A (0.44) | TAAR1LTB4RLTB4R2HTTSMN1; SMN2 | |
| SCHEMBL31443083 | 0.71 | ALDH1A1 (0.47) | ALDH1A1RAB9AHTTSMN1; SMN2KDM4E | |
| SCHEMBL3863448 | 0.70 | LTB4R (0.52) | TAAR1LTB4RLTB4R2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234079-B | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-113234079-A | Nucleoside analogs as PRMT5 inhibitors | 上海湃隆生物科技有限公司 | 2021-08-10 | — | — | CN | disclosed |