Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172439 | 0.91 | MMP2 (0.38) | L3MBTL1ALDH1A1MAPTHSD11B1LMNA | |
| SCHEMBL26638295 | 0.91 | MMP2 (0.38) | L3MBTL1ALDH1A1MAPTHSD11B1LMNA | |
| SCHEMBL28634279 | 0.87 | L3MBTL1 (0.34) | L3MBTL1ALDH1A1MAPTHSD11B1LMNA | |
| SCHEMBL14644191 | 0.86 | MAPT (0.38) | L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL14643453 | 0.86 | MAPT (0.38) | L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL9991927 | 0.86 | CDK2 (0.39) | L3MBTL1TSHRALDH1A1MAPTHSD11B1 | |
| SCHEMBL28637052 | 0.86 | L3MBTL1 (0.39) | L3MBTL1POLBTSHRALDH1A1LMNA | |
| SCHEMBL30798172 | 0.85 | NAMPT (0.36) | L3MBTL1POLBALDH1A1MAPTLMNA | |
| SCHEMBL30797961 | 0.85 | NAMPT (0.36) | L3MBTL1POLBALDH1A1MAPTLMNA | |
| SCHEMBL26638008 | 0.85 | NAMPT (0.36) | L3MBTL1POLBALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396150-A | Tricyclic JANUS kinase 1 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2021-09-14 | — | — | CN | disclosed |