Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172444 | 0.91 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1HTR6CCR6KMT2A | |
| SCHEMBL26638293 | 0.91 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1HTR6CCR6KMT2A | |
| SCHEMBL28637033 | 0.87 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1HTR6PTPN11CCR6 | |
| SCHEMBL28628580 | 0.87 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1HTR6PTPN11CCR6 | |
| SCHEMBL28634161 | 0.86 | L3MBTL1 (0.37) | L3MBTL1TSHRALDH1A1POLBPTPN11 | |
| SCHEMBL9989458 | 0.85 | L3MBTL1 (0.41) | L3MBTL1TSHRALDH1A1HTR6CCR6 | |
| SCHEMBL30798285 | 0.84 | KMT2A (0.38) | L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL26638100 | 0.84 | KMT2A (0.38) | L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL26638016 | 0.84 | KMT2A (0.38) | L3MBTL1POLBMEN1KMT2A | |
| SCHEMBL30811342 | 0.80 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1POLBHTR6CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113396150-A | Tricyclic JANUS kinase 1 inhibitors, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2021-09-14 | — | — | CN | disclosed |