SCHEMBL28634174

SCHEMBL28634174

N#CN1CCc2cc(Cl)ccc2C1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.42
HTR2C P28335 2/20 0.42
HTR2B P41595 2/20 0.42
OTUD7B Q6GQQ9 1/20 0.41
NOTUM Q6P988 2/20 0.41
AKR1C3 P42330 1/20 0.39
AKR1C1 Q04828 1/20 0.39
HSD17B3 P37058 2/20 0.37
ACHE P22303 1/20 0.37
ACACB O00763 1/20 0.36
PNMT P11086 1/20 0.36
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
ROCK1 Q13464 1/20 0.35
USP30 Q70CQ3 3/20 0.35
SRD5A1 P18405 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28632465 0.79 CARM1 (0.42) HTR2AHTR2CHTR2BAKR1C3HSD17B3
SCHEMBL30043742 0.76 MAOA (0.52) NOTUMDRD2DRD3USP30
SCHEMBL2327219 0.76 MAOA (0.52) NOTUMDRD2DRD3USP30
SCHEMBL28615258 0.76 DRD1 (0.56) OTUD7BNOTUMDRD2DRD3USP30
SCHEMBL31020323 0.73 HTR2A (0.46) HTR2AHTR2CHTR2BNOTUMAKR1C3
SCHEMBL6883015 0.73 MAOA (0.59) HTR2AHTR2CHTR2BDRD2DRD3
SCHEMBL10534781 0.70 CETP (0.48) HTR2AHTR2CHTR2BAKR1C3ACHE
SCHEMBL160943 0.70 HTR2A (0.55) HTR2AHTR2CHTR2BNOTUMPNMT
SCHEMBL24755229 0.69 HTR2A (0.42) HTR2AHTR2CHTR2BNOTUMAKR1C3
SCHEMBL6369521 0.69 PNMT (0.55) HTR2AHTR2CHTR2BACACBPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113200912-B Method for synthesizing cyanamide 南昌大学 2022-12-06 CN disclosed
CN-113200912-A Method for synthesizing cyanamide 南昌大学 2021-08-03 CN disclosed