Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463513 | 0.83 | KDM4E (0.50) | HPGDKDM4EALDH1A1POLBLMNA | |
| SCHEMBL28630088 | 0.81 | KDM4E (0.43) | HPGDKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL28619853 | 0.80 | KDM4E (0.42) | HPGDKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL19463979 | 0.78 | KEAP1 (0.40) | KDM4EALDH1A1TDP1L3MBTL1POLB | |
| SCHEMBL19492615 | 0.78 | KDM4E (0.40) | HPGDKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL19464294 | 0.78 | KDM4E (0.40) | HPGDKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL19492870 | 0.78 | TDP1 (0.41) | HPGDKDM4EALDH1A1TDP1L3MBTL1 | |
| SCHEMBL19464269 | 0.77 | ALDH1A1 (0.40) | KDM4EALDH1A1TDP1L3MBTL1POLB | |
| SCHEMBL20768125 | 0.73 | MAPT (0.41) | HPGDKDM4EALDH1A1POLBLMNA | |
| SCHEMBL19463237 | 0.73 | ALDH1A1 (0.45) | HPGDKDM4EALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |