Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630088 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL19492615 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1TDP1NR3C1SMN1; SMN2 | |
| SCHEMBL19492870 | 0.80 | TDP1 (0.41) | KDM4EALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL28634209 | 0.80 | HPGD (0.43) | KDM4EALDH1A1TDP1NR3C1SMN1; SMN2 | |
| SCHEMBL19464294 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1TDP1SMN1; SMN2MAPT | |
| SCHEMBL19464269 | 0.79 | ALDH1A1 (0.40) | KDM4EALDH1A1TDP1NR3C1SMN1; SMN2 | |
| SCHEMBL19463979 | 0.78 | KEAP1 (0.40) | KDM4EALDH1A1TDP1NR3C1SMN1; SMN2 | |
| SCHEMBL19463237 | 0.75 | ALDH1A1 (0.45) | KDM4EALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL19492644 | 0.71 | ALDH1A1 (0.40) | KDM4EALDH1A1TDP1NR3C1SMN1; SMN2 | |
| SCHEMBL28614649 | 0.70 | CYP1A2 (0.59) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |