Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405805 | 1.00 | KDM1A (0.43) | KDM1ASLC6A4CCR5MAOBMAOA | |
| SCHEMBL30079795 | 0.92 | KDM1A (0.44) | KDM1ASLC6A4CCR5MAOBMAOA | |
| SCHEMBL21893210 | 0.92 | KDM1A (0.44) | KDM1ASLC6A4CCR5MAOBMAOA | |
| SCHEMBL11128563 | 0.85 | BCHE (0.41) | SLC6A4MAOBMAOARAB9ANPC1 | |
| SCHEMBL28645951 | 0.81 | MAOB (0.43) | SLC6A4MAOBMAOARAB9AALDH1A1 | |
| SCHEMBL31405801 | 0.81 | MAOB (0.43) | SLC6A4MAOBMAOARAB9AALDH1A1 | |
| SCHEMBL11124024 | 0.79 | PIN1 (0.40) | SLC6A4MAOBMAOARAB9AALDH1A1 | |
| SCHEMBL28498402 | 0.77 | RXRB (0.47) | HTR1A | |
| SCHEMBL21588917 | 0.76 | LTA4H (0.43) | MAOBMAOARAB9AALDH1A1HTR2C | |
| SCHEMBL29814352 | 0.76 | LTA4H (0.43) | MAOBMAOARAB9AALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444102-A | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2021-09-28 | — | — | CN | disclosed |