Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349002 | 0.82 | MAPT (0.51) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11322352 | 0.81 | MAPT (0.49) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30148008 | 0.78 | SMN1; SMN2 (0.67) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL6694651 | 0.78 | SMN1; SMN2 (0.67) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL7839911 | 0.77 | ALDH1A1 (0.46) | MAPTRAB9AHTTSMN1; SMN2GAA | |
| SCHEMBL28349080 | 0.77 | KMT2A (0.58) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL3211806 | 0.77 | POLB (0.67) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL1029643 | 0.77 | ALDH1A1 (0.55) | MAPTRAB9AMEN1KMT2AHTT | |
| SCHEMBL5958700 | 0.76 | SMN1; SMN2 (0.42) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4938228 | 0.76 | KMT2A (0.62) | MAPTRAB9AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416139-B | 4-fluorine substituted aryl amine compound and synthetic method thereof | 江苏笃行致远新材料科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-113416139-A | 4-fluorine substituted aryl amine compound and synthetic method thereof | 江苏笃行致远新材料科技有限公司 | 2021-09-21 | — | — | CN | disclosed |