Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MB | P02144 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349002 | 0.84 | MAPT (0.51) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL28634302 | 0.81 | MAPT (0.49) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL28349080 | 0.78 | KMT2A (0.58) | MAPTNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL28707102 | 0.78 | MIF (0.40) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL2896946 | 0.77 | POLB (0.71) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL10390825 | 0.77 | POLB (0.41) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL4938228 | 0.77 | KMT2A (0.62) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL29651063 | 0.77 | KMT2A (0.62) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL3624295 | 0.76 | ALDH1A1 (0.44) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL28346183 | 0.76 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265909-A | Inhibiting platelet aggregation with substituted acetanilides | SOUTH CAROLINA, MEDICAL UNIVERSITY OF | 1981-05-05 | — | — | US | disclosed |
| US-4186209-A | Substituted acetanilides as medicinals | SOUTH CAROLINA, MEDICAL UNIVERSITY OF | 1980-01-29 | — | — | US | disclosed |