Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322352 | 0.84 | MAPT (0.49) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL28634302 | 0.82 | MAPT (0.49) | MAPTPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL3624295 | 0.81 | ALDH1A1 (0.44) | MAPTPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL28349080 | 0.80 | KMT2A (0.58) | MAPTPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL2306741 | 0.79 | KMT2A (0.69) | KMT2AALDH1A1MEN1HPGDNPC1 | |
| SCHEMBL10390825 | 0.79 | POLB (0.41) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL4938228 | 0.79 | KMT2A (0.62) | MAPTPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL18131322 | 0.79 | TDP1 (0.52) | MAPTKMT2AALDH1A1MEN1TDP1 | |
| SCHEMBL29651063 | 0.79 | KMT2A (0.62) | MAPTPKMKMT2AALDH1A1MEN1 | |
| SCHEMBL28279022 | 0.78 | KCNMA1 (0.63) | MAPTPKMKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698373-A | Preparation method of N- (2- (methylthio) phenyl) acetamide compound and purification method thereof | 温州大学 | 2020-01-17 | — | — | CN | disclosed |