Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187921 | 0.79 | MAPT (0.41) | — | |
| SCHEMBL6025891 | 0.79 | MAPK1 (0.36) | — | |
| SCHEMBL28642187 | 0.75 | LMNA (0.33) | IKBKBMAP3K14 | |
| SCHEMBL11545681 | 0.69 | TSHR (0.41) | — | |
| SCHEMBL16654865 | 0.67 | TSHR (0.40) | — | |
| SCHEMBL31613005 | 0.67 | PTGS2 (0.35) | IKBKBMAP3K14 | |
| SCHEMBL5277792 | 0.65 | GRM2 (0.36) | — | |
| SCHEMBL23208824 | 0.65 | PTPN11 (0.33) | — | |
| SCHEMBL31319649 | 0.64 | CYP11B2 (0.42) | — | |
| SCHEMBL16911057 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357905-B | Macrocyclic derivatives as protein kinase inhibitors, and preparation method and application thereof | 武汉誉祥医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110357905-A | Big ring analog derivative and its preparation method and application as kinases inhibitor | 武汉宇科源医药生物科技有限公司 | 2019-10-22 | — | — | CN | disclosed |