SCHEMBL28634694

SCHEMBL28634694

O=c1c(O)c(O)c2c(=O)c3ccccc3c(=O)c=2c1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.38
▸ SMN1; SMN2 Q16637 4/20 0.38
▸ MAPT P10636 3/20 0.38
▸ GAA P10253 3/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ KDM4E B2RXH2 6/20 0.36
▸ IDE P14735 1/20 0.36
▸ MPI P34949 1/20 0.36
▸ CACNA1B Q00975 1/20 0.36
▸ APBA1 Q02410 1/20 0.36
▸ HPGD P15428 4/20 0.36
▸ GLA P06280 3/20 0.36
▸ HSD17B10 Q99714 3/20 0.36
▸ HTT P42858 2/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ CYP3A4 P08684 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8856454 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MAPTGAANPC1
SCHEMBL5316204 0.75 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPTGAANPC1
SCHEMBL20783635 0.75 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2MAPTGAANPC1
SCHEMBL819204 0.73 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2MAPTGAANPC1
SCHEMBL15732920 0.72 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2MAPTGAANPC1
SCHEMBL27418232 0.68 S100A4 (0.44) ALDH1A1SMN1; SMN2MAPTGAANPC1
SCHEMBL4311602 0.68 — —
SCHEMBL927812 0.68 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2MAPTGAANPC1
Biphenyl SCHEMBL5711843 0.67 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPTKDM4EHPGD
SCHEMBL3275756 0.67 PAX8 (0.44) ALDH1A1SMN1; SMN2MAPTGAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569846-A HMGB1 protein derivatives for removal of biofilm 国家儿童医院研究所 2025-03-07 — — CN disclosed
CN-118994395-A VISTA receptor 皮埃尔法布雷医药公司 2024-11-22 — — CN disclosed
CN-118459590-A Anti-BTN 3A antibodies and their use in the treatment of cancer or infectious disorders 感应检查疗法公司 2024-08-09 — — CN disclosed
CN-118307674-A Antibody molecules against CD73 and uses thereof 诺华股份有限公司 2024-07-09 — — CN disclosed
CN-111630069-B Human antibodies to Thomsen-non-velle (Tn) antigen 勃林格殷格翰国际有限公司 2024-05-31 — — CN disclosed
CN-113286819-B Anti-BTN 3A antibodies and their use in the treatment of cancer or infectious disorders 感应检查疗法公司 2024-05-24 — — CN disclosed
CN-110785187-B Antibody molecules against CD73 and uses thereof 诺华股份有限公司 2024-04-05 — — CN disclosed
CN-112153987-B Antibody-drug conjugates and their use for the treatment of cancer 伊纳泰里斯公司 2024-01-09 — — CN disclosed
CN-112236456-B Novel bispecific PD-1/LAG-3 antibody molecules 上海药明生物技术有限公司 2023-12-22 — — CN disclosed
CN-116675777-A Multispecific ligand binding molecules comprising complement inhibition domains and uses thereof 苏州光度生物科技有限公司 2023-09-01 — — CN disclosed
CN-116162148-A Multispecific ligand binding molecules and uses thereof 苏州光度生物科技有限公司 2023-05-26 — — CN disclosed
CN-116059351-A Agonistic antibodies that bind human CD40 and uses thereof 塞德斯医疗公司 2023-05-05 — — CN disclosed
CN-115803047-A Recombinant sialidases, sialidase fusion proteins with reduced protease sensitivity and methods of use thereof 帕利昂制药有限公司 2023-03-14 — — CN disclosed
CN-109071665-B Agonistic antibodies that bind human CD40 and uses thereof 塞德斯医疗公司 2022-11-01 — — CN disclosed
CN-115023439-A anti-CD 73 antibodies 西福根有限公司 2022-09-06 — — CN disclosed
CN-114630838-A Novel anti-CD 25 antibodies 法国国家健康和医学研究院 2022-06-14 — — CN disclosed
CN-114302897-A sialidase-HER 2 antibody fusion proteins and methods of use thereof 帕利昂制药有限公司 2022-04-08 — — CN disclosed
CN-114269937-A Recombinant sialidases and methods of use thereof 帕利昂制药有限公司 2022-04-01 — — CN disclosed
CN-114258431-A Recombinant human sialidases, sialidase fusion proteins, and methods of use thereof 帕利昂制药有限公司 2022-03-29 — — CN disclosed
CN-112654394-A Antibody molecules against complement component 5 and uses thereof 阿塔盖有限责任公司 2021-04-13 — — CN disclosed
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