Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28031985 | 0.91 | PNMT (0.56) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL221400 | 0.89 | PNMT (0.58) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL30497776 | 0.89 | PNMT (0.58) | PNMTHTR7HTR2BNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2866030 | 0.87 | PNMT (0.56) | PNMTHTR7HTR2BNPC1RAB9A | |
| Bromide SCHEMBL28349432 | 0.87 | PNMT (0.56) | PNMTHTR7HTR2BNPC1RAB9A | |
| Biphenyl SCHEMBL28377104 | 0.86 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| Phenol SCHEMBL27918871 | 0.83 | PNMT (0.46) | PNMTHTR7HTR2BNPC1RAB9A | |
| Dimethylamine SCHEMBL28473739 | 0.82 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| Phenol SCHEMBL29142512 | 0.82 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL27449640 | 0.81 | PNMT (0.54) | PNMTHTR7HTR2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | claimed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | claimed |
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113336670-B | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | disclosed |
| CN-113336670-A | Axial chiral fluorenamine-phenol derivative and preparation method thereof | 河南大学 | 2021-09-03 | — | — | CN | disclosed |