Benzene

Benzene

SCHEMBL28031985

Nc1cccc2c1Cc1ccccc1-2.c1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.56
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
HTR7 P34969 1/20 0.45
HTR2B P41595 1/20 0.45
ACHE P22303 2/20 0.45
BCHE P06276 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.42
HSD17B10 Q99714 1/20 0.41
KDR P35968 2/20 0.41
CD44 P16070 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30497776 0.98 PNMT (0.58) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL221400 0.98 PNMT (0.58) PNMTALDH1A1NPC1RAB9AKDM4E
Hydrochloric Acid SCHEMBL2866030 0.96 PNMT (0.56) PNMTALDH1A1NPC1RAB9AKDM4E
Bromide SCHEMBL28349432 0.96 PNMT (0.56) PNMTALDH1A1NPC1RAB9AKDM4E
Biphenyl SCHEMBL28377104 0.94 PNMT (0.51) PNMTALDH1A1NPC1RAB9AKDM4E
Phenol SCHEMBL28634798 0.91 PNMT (0.53) PNMTALDH1A1NPC1RAB9AKDM4E
Dimethylamine SCHEMBL28473739 0.90 PNMT (0.51) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL3630935 0.88 PNMT (0.56) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL8436976 0.87 PNMT (0.49) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL21142139 0.86 PNMT (0.55) PNMTALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104854082-A 3,5, N-trihydroxy alkanamide and its derivative, and its preparation method and application ACADEMIA SINICA 2015-08-19 CN disclosed