SCHEMBL221400

SCHEMBL221400

Nc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.58
ALDH1A1 P00352 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HTR7 P34969 1/20 0.46
HTR2B P41595 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.44
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
ACHE P22303 3/20 0.42
BCHE P06276 2/20 0.42
MAOA P21397 1/20 0.41
CD44 P16070 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30497776 1.00 PNMT (0.58) PNMTALDH1A1NPC1RAB9AKDM4E
Hydrochloric Acid SCHEMBL2866030 0.98 PNMT (0.56) PNMTALDH1A1NPC1RAB9AKDM4E
Bromide SCHEMBL28349432 0.98 PNMT (0.56) PNMTALDH1A1NPC1RAB9AKDM4E
Dimethylamine SCHEMBL28473739 0.92 PNMT (0.51) PNMTALDH1A1NPC1RAB9AKDM4E
Biphenyl SCHEMBL28377104 0.92 PNMT (0.51) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL3630935 0.89 PNMT (0.56) PNMTALDH1A1NPC1RAB9AKDM4E
Phenol SCHEMBL28634798 0.89 PNMT (0.53) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL8436976 0.89 PNMT (0.49) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL21142139 0.88 PNMT (0.55) PNMTALDH1A1NPC1RAB9AKDM4E
SCHEMBL283174 0.86 PNMT (0.53) PNMTALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 994 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661980-A Resin composition, composite material, preparation method and build-up film 广东盈骅新材料科技有限公司 2025-03-21 CN claimed
US-20250098528-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2025-03-20 US claimed
CN-119569585-A Organic electroluminescent compound and organic electroluminescent device 杜邦特种材料韩国有限公司 2025-03-07 CN claimed
US-12188350-B2 Fluorescent dye oil tracer compositions SAUDI ARABIAN OIL COMPANY (SA) 2025-01-07 US claimed
CN-118511672-A Organic electronic component with hybrid host system 默克专利有限公司 2024-08-16 CN claimed
US-11957046-B2 Electroluminescent device, and display device comprising thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-04-09 US claimed
CN-117343325-A Polyimide, transparent polyimide film material and preparation method thereof 株洲时代新材料科技股份有限公司 2024-01-05 CN claimed
US-20230399942-A1 FLUORESCENT DYE OIL TRACER COMPOSITIONS SAUDI ARABIAN OIL COMPANY (SA) 2023-12-14 US claimed
CN-117121655-A Material for organic electroluminescent device 默克专利有限公司 2023-11-24 CN claimed
CN-117099507-A Material for organic electroluminescent device 默克专利有限公司 2023-11-21 CN claimed
US-6007917-A FOR MAKING LIGHTWEIGHT, HIGH STRENGH AIRCRAFT COMPONENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-12-28 US claimed
EP-0863877-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INST (US) 1999-07-21 EP claimed
US-5916899-A SOLID PHASE SYNTHESIS, REACTING PROTECTED AMINO ACID WITH SOLID SUPPORT; FORMING IMINE BY REACTION WITH ALDEHYDE, CYCLIZATION WITH ANHYDRIDE, CLEAVAGE AND DEPROTECTION. TREGA BIOSCIENCES, INC. (US) 1999-06-29 US claimed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US claimed
EP-0863877-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1998-09-16 EP claimed
EP-0851887-A1 EPOXY RESIN COMPOSITIONS, PREPREGS, CURED COMPOSITES, AND METHODS OF MAKING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-07-08 EP claimed
US-5728755-A EXHIBIT TACK AND GOOD SHELF LIFE, LITTLE RESIN MIGRATION AND GLASS TRANSITION TEMPERATURE SIMILAR TO THOSE CURED NEAT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-17 US claimed
US-5635582-A Magnetic copolymer, a method of manufacture and applications thereof ALCATEL ALSTHOM COMPAGNIE GENERALE D'ELECTRICITE (FR) 1997-06-03 US claimed
WO-1997016428-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-05-09 WO claimed
WO-1997011112-A1 EPOXY RESIN COMPOSITIONS, PREPREGS, CURED COMPOSITES, AND METHODS OF MAKING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250098528-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE SLCO2A1, SLCO4C1, SLCO2B1 PNMT 249/4885ALDH1A1 381/4885NPC1 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.