Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | GRM5 | P41594 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28631701 | 0.85 | KMT2A (0.43) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL28634855 | 0.82 | CTDSP1 (0.61) | MEN1KMT2ACTDSP1KDM4EALDH1A1 | |
| SCHEMBL28631820 | 0.80 | CYP1A2 (0.51) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL1135252 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL11831057 | 0.77 | CTDSP1 (0.49) | MEN1KMT2ACTDSP1KDM4EALDH1A1 | |
| SCHEMBL28547028 | 0.75 | MEN1 (0.49) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29684288 | 0.74 | KMT2A (0.53) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL869497 | 0.74 | KMT2A (0.53) | MEN1KMT2AKDM4EALDH1A1OPRM1 | |
| SCHEMBL28631700 | 0.72 | KMT2A (0.47) | MEN1KMT2ACTDSP1KDM4EALDH1A1 | |
| SCHEMBL6900384 | 0.71 | P2RX7 (0.46) | MEN1KMT2AKDM4EALDH1A1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761986-B | Tricyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-10-08 | — | — | CN | disclosed |