Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.82 |
| ▸ | TP53 | P04637 | 3/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.73 |
| ▸ | STS | P08842 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.62 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27493025 | 0.90 | SMN1; SMN2 (1.00) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL30540840 | 0.90 | SMN1; SMN2 (1.00) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL27609731 | 0.86 | ABCB1 (0.69) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL28635129 | 0.85 | ABCB1 (0.71) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| 6-Methoxyflavone SCHEMBL30799564 | 0.85 | ABCB1 (1.00) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| 6-Methoxyflavone SCHEMBL312059 | 0.85 | ABCB1 (1.00) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| 6-Methoxyflavone SCHEMBL28930176 | 0.85 | ABCB1 (1.00) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| 6-Methoxyflavone SCHEMBL28301080 | 0.83 | ABCB1 (0.97) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL28646380 | 0.83 | ABCB1 (0.68) | MAPTTP53CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL28647882 | 0.82 | ABCB1 (0.67) | MAPTTP53CYP3A4ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512018-B | Flavonoid compound and preparation method and application thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-113512018-A | Flavonoid compound and preparation method and application thereof | 合肥工业大学 | 2021-10-19 | — | — | CN | disclosed |