Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31069248 | 0.83 | MAPT (0.44) | POLBMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL23645328 | 0.83 | MAPT (0.44) | POLBMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL31069233 | 0.82 | NR4A2 (0.40) | POLBMEN1KMT2AHDAC6MTHFD2 | |
| SCHEMBL23645315 | 0.82 | NR4A2 (0.40) | POLBMEN1KMT2AHDAC6MTHFD2 | |
| SCHEMBL23645366 | 0.81 | TGFBR1 (0.49) | MEN1KMT2AHDAC6ALDH1A1HSD17B10 | |
| SCHEMBL31069264 | 0.81 | TGFBR1 (0.49) | MEN1KMT2AHDAC6ALDH1A1HSD17B10 | |
| SCHEMBL29724054 | 0.77 | TGFBR1 (0.53) | MEN1KMT2AHDAC6ALDH1A1HSD17B10 | |
| SCHEMBL19909627 | 0.73 | MAPK1 (0.43) | POLBMEN1KMT2AHDAC6MTHFD2 | |
| SCHEMBL23652754 | 0.71 | HDAC6 (0.39) | POLBMEN1KMT2AHDAC6MTHFD2 | |
| SCHEMBL21810872 | 0.69 | MAPT (0.43) | POLBMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-A | Novel heteroatom aromatic amide derivative and drug containing the same | 科研制药株式会社 | 2021-04-20 | — | — | CN | disclosed |