Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.37 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645328 | 1.00 | MAPT (0.44) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL21810872 | 0.86 | MAPT (0.43) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL31069250 | 0.84 | TGFBR1 (0.46) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL23645429 | 0.84 | TGFBR1 (0.46) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL28635156 | 0.83 | POLB (0.44) | ALDH1A1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL12683108 | 0.75 | GRM5 (0.47) | ALDH1A1RAB9ANPC1KDM4EHSD17B10 | |
| SCHEMBL23645338 | 0.73 | MAPT (0.53) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL21357773 | 0.73 | MAPT (0.53) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL23645315 | 0.71 | NR4A2 (0.40) | MAPTALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL31069233 | 0.71 | NR4A2 (0.40) | MAPTALDH1A1RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-B | Novel heteroatom aromatic amide derivative and pharmaceutical agent containing same | 科研制药株式会社 | 2024-08-20 | — | — | CN | disclosed |