Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645315 | 1.00 | NR4A2 (0.40) | NR4A2DHODHMEN1KMT2AHDAC6 | |
| SCHEMBL21810872 | 0.86 | MAPT (0.43) | MEN1KMT2ATGFBR1RAB9AMAPT | |
| SCHEMBL28635156 | 0.82 | POLB (0.44) | MEN1KMT2AHDAC6RAB9ARORC | |
| SCHEMBL31069264 | 0.78 | TGFBR1 (0.49) | MEN1KMT2AHDAC6TGFBR1RAB9A | |
| SCHEMBL23645366 | 0.78 | TGFBR1 (0.49) | MEN1KMT2AHDAC6TGFBR1RAB9A | |
| SCHEMBL29724054 | 0.74 | TGFBR1 (0.53) | MEN1KMT2AHDAC6TGFBR1RAB9A | |
| SCHEMBL23645385 | 0.73 | MAPT (0.42) | MAPTTP53POLBLMNA | |
| SCHEMBL23645382 | 0.73 | MAPT (0.42) | MAPTTP53POLBLMNA | |
| SCHEMBL31069238 | 0.73 | MAPT (0.42) | MAPTTP53POLBLMNA | |
| SCHEMBL23645328 | 0.71 | MAPT (0.44) | MEN1KMT2ARAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-B | Novel heteroatom aromatic amide derivative and pharmaceutical agent containing same | 科研制药株式会社 | 2024-08-20 | — | — | CN | disclosed |