Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643991 | 1.00 | ATM (0.43) | ATMHCAR2THRBTSHRLMNA | |
| SCHEMBL28635181 | 0.92 | HCAR2 (0.53) | ATMHCAR2THRBTSHRLMNA | |
| SCHEMBL3292973 | 0.83 | TSHR (0.57) | THRBTSHRLMNATDP1ALDH1A1 | |
| SCHEMBL29277897 | 0.83 | TSHR (0.57) | THRBTSHRLMNATDP1ALDH1A1 | |
| SCHEMBL14672303 | 0.79 | THRB (0.43) | THRBLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL8661899 | 0.79 | ATM (0.48) | ATMHCAR2TSHRLMNATDP1 | |
| SCHEMBL2488159 | 0.79 | ATM (0.48) | ATMHCAR2TSHRLMNATDP1 | |
| SCHEMBL14672336 | 0.79 | THRB (0.43) | THRBLMNAALDH1A1KDM4EDUSP3 | |
| Ethane SCHEMBL10710106 | 0.78 | ATM (0.53) | ATMHCAR2TSHRLMNATDP1 | |
| SCHEMBL9542151 | 0.77 | TSHR (0.50) | THRBTSHRLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490489-A | Monomethyl fumarate-carrier conjugates and methods of use thereof | 旗舰创业创新五公司 | 2021-10-08 | — | — | CN | disclosed |