SCHEMBL8940099

SCHEMBL8940099

O=C(O)/C=C/C(=O)OCC(O)CO

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.50
KDM4E B2RXH2 1/20 0.40
DUSP3 P51452 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 1/20 0.40
DGKA P23743 1/20 0.37
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
FAAH O00519 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8661906 1.00 HCAR2 (0.50) HCAR2KDM4EDUSP3MEN1KMT2A
SCHEMBL4439683 1.00 HCAR2 (0.50) HCAR2KDM4EDUSP3MEN1KMT2A
SCHEMBL8940101 0.92 LMNA (0.44) HCAR2KDM4EDUSP3MEN1KMT2A
SCHEMBL6665040 0.92 LMNA (0.44) HCAR2KDM4EDUSP3MEN1KMT2A
SCHEMBL4439685 0.92 LMNA (0.44) HCAR2KDM4EDUSP3MEN1KMT2A
SCHEMBL15794290 0.90 HCAR2 (0.56) HCAR2KDM4ETSHRTP53EGLN1
SCHEMBL15794287 0.90 HCAR2 (0.56) HCAR2KDM4ETSHRTP53EGLN1
Hexadecane SCHEMBL28028773 0.88 HCAR2 (0.61) HCAR2KDM4EDUSP3MEN1KMT2A
SCHEMBL17172093 0.86 LMNA (0.41) HCAR2KDM4EDUSP3MEN1KMT2A
Maleic Acid SCHEMBL28185920 0.86 LMNA (0.41) HCAR2KDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119235804-A Carbamazepine pharmaceutical composition and preparation method and application thereof 上海则正医药科技股份有限公司 2025-01-03 CN claimed
US-12090254-B2 Composite tubular material prepared from extracellular matrix and synthetic polymer, and preparation method thereof NANKAI UNIVERSITY (CN) 2024-09-17 US claimed
US-20240238206-A1 LOSARTAN-CONTAINING MICRO TABLET FOR PEDIATRIC APPLICATIONS Midas Pharma GmbH (DE) 2024-07-18 US claimed
CN-118055759-A Miniature tablet containing losartan for pediatric use 米达斯制药有限责任公司 2024-05-17 CN claimed
EP-4135668-B1 SOLID ORAL DOSAGE FORM COMPRISING POMALIDOMIDE TECNIMEDE SOCIEDADE TECNICO MEDICINAL SA (PT) 2024-04-17 EP claimed
EP-4333816-A1 LOSARTAN-CONTAINING MICRO TABLET FOR PEDIATRIC APPLICATIONS Midas Pharma GmbH (DE) 2024-03-13 EP claimed
US-20240024539-A1 COMPOSITE TUBULAR MATERIAL PREPARED FROM EXTRACELLULAR MATRIX AND SYNTHETIC POLYMER, AND PREPARATION METHOD THEREOF UNIV NANKAI (CN) 2024-01-25 US claimed
CN-116947642-A Long-residence polyalcohol hair care raw material molecule and preparation and application thereof 江南大学 2023-10-27 CN claimed
CN-113336929-B Degradable photocrosslinking triblock copolymer and preparation method and application thereof 中山大学 2023-07-11 CN claimed
WO-2023104096-A1 POROUS MICROCARRIER AND PREPARATION METHOD THEREFOR 中科睿极(深圳)医学科技有限公司 2023-06-15 WO claimed
EP-3429561-A1 FIXED DOSED PHARMACEUTICAL COMPOSITION COMPRISING AMIODIPINE, CANDESARTAN CILEXETIL AND HYDROCHLOROTHIAZIDE FOR THE TREATMENT OF HYPERTENSION. Midas Pharma GmbH (DE) 2019-01-23 EP claimed
US-20180243283-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS GRINDEKS, A JOINT STOCK COMPANY (LV) 2018-08-30 US claimed
US-9895325-B2 Tablet composition comprising cinacalcet hydrochloride SYNTHON B.V. (NL) 2018-02-20 US claimed
WO-2017158094-A1 FIXED DOSED PHARMACEUTICAL COMPOSITION COMPRISING AMIODIPINE, CANDESARTAN CILEXETIL AND HYDROCHLOROTHIAZIDE FOR THE TREATMENT OF HYPERTENSION. K.H.S. PHARMA HOLDING GMBH (DE) 2017-09-21 WO claimed
EP-3219309-A1 FIXED DOSED PHARMACEUTICAL COMPOSITION COMPRISING AMLODIPINE, CANDESARTAN CILEXETIL AND HYDROCHLOROTHIAZIDE FOR THE TREATMENT OF HYPERTENSION K.H.S. Pharma Holding GmbH (DE) 2017-09-20 EP claimed
WO-2017032870-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS GRINDEKS, A JOINT STOCK COMPANY (LV) 2017-03-02 WO claimed
EP-3135275-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS Grindeks, A Joint Stock Company (LV) 2017-03-01 EP claimed
EP-3002006-A1 Pharmaceutical composition capable for the incorporation Febuxostat in the crystalline modifications F10, II, G and A Bluepharma - Industria Farmacêutica, S.A. (PT) 2016-04-06 EP claimed
WO-2014029953-A1 HOT MELT EXTRUDED (HME) PHARMACEUTICAL COMPOSITION OF CINACALCET CIPLA LIMITED (IN) 2014-02-27 WO claimed
EP-0516141-B1 Pharmaceutical controlled-release composition with bioadhesive properties RECORDATI CHEM PHARM (CH) 1996-08-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180243283-A1 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS RPL7, RPL26, PDCD2L HCAR2 3609/4885KDM4E 1761/4885DUSP3 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.