Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580780 | 0.86 | FFAR1 (0.55) | FFAR1LMNAL3MBTL1KEAP1FFAR4 | |
| SCHEMBL19294596 | 0.86 | FFAR1 (0.55) | FFAR1LMNAL3MBTL1KEAP1FFAR4 | |
| SCHEMBL3584403 | 0.83 | KEAP1 (0.63) | FFAR1KEAP1FFAR4HDAC3MAPK1 | |
| SCHEMBL3584933 | 0.82 | FFAR1 (0.51) | FFAR1LMNAL3MBTL1KEAP1FFAR4 | |
| SCHEMBL3594094 | 0.82 | FFAR1 (0.56) | FFAR1LMNAL3MBTL1KEAP1FFAR4 | |
| SCHEMBL13886150 | 0.82 | L3MBTL1 (0.56) | FFAR1LMNAL3MBTL1FFAR4 | |
| SCHEMBL3364938 | 0.81 | FFAR1 (0.65) | FFAR1LMNAL3MBTL1KEAP1CES2 | |
| SCHEMBL18741285 | 0.78 | MTNR1A (0.34) | FFAR1CES2CES1HDAC8CA1 | |
| SCHEMBL11724879 | 0.77 | SMN1; SMN2 (0.67) | FFAR1LMNAKEAP1CES2CES1 | |
| SCHEMBL34466316 | 0.76 | FFAR1 (0.53) | FFAR1FFAR4HDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849008-B | Octahydrocyclopenta [ c ] pyrrole derivative, preparation method and medical application thereof | 四川海思科制药有限公司 | 2021-04-09 | — | — | CN | disclosed |