Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | ASPH | Q12797 | 3/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.48 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083217 | 0.98 | KDM4E (0.50) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL9318758 | 0.83 | KDM4E (0.60) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL19857491 | 0.83 | GABRP (0.63) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL12384971 | 0.81 | UHRF1 (0.52) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL935259 | 0.81 | KMO (0.51) | KDM4EASPHKDM8P4HTMP4HA1 | |
| Hydrochloric Acid SCHEMBL23884908 | 0.81 | KDM4E (0.58) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL12489210 | 0.81 | GABRP (0.47) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL232024 | 0.81 | KDM4E (0.52) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL1180456 | 0.81 | KDM4E (0.52) | KDM4EASPHKDM8P4HTMP4HA1 | |
| SCHEMBL20161506 | 0.81 | ASPH (0.44) | KDM4EASPHKDM8P4HTMP4HA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349947-B | Tetrahydroindazoles and pharmaceutical uses thereof | 格纳赛治疗有限公司 | 2021-10-01 | — | — | CN | disclosed |