Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | PYGM | P11217 | 3/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.51 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685780 | 0.99 | HPGD (0.60) | HPGDPAX8PYGMSLC28A1SLC28A2 | |
| SCHEMBL31685347 | 0.87 | HPGD (0.48) | HPGDPAX8PYGMTK2 | |
| SCHEMBL31685360 | 0.85 | ADORA1 (0.51) | HPGD | |
| SCHEMBL31685712 | 0.84 | IMPDH2 (0.66) | — | |
| SCHEMBL7152626 | 0.82 | PAX8 (0.52) | HPGDPAX8SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL4581304 | 0.81 | HPGD (0.54) | HPGDPAX8SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL4778753 | 0.81 | PAX8 (0.53) | HPGDPAX8SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL4778770 | 0.81 | PAX8 (0.53) | HPGDPAX8SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10726368 | 0.80 | HPGD (0.54) | HPGDPAX8PYGMSLC28A1SLC28A2 | |
| SCHEMBL31685373 | 0.80 | TK1 (0.56) | LMNADNMT1BLMPMP22TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113433239-A | Marker and kit for diagnosing cardia cancer | 郑州大学第一附属医院 | 2021-09-24 | — | — | CN | disclosed |