Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23624207 | 0.83 | RPS6KA5 (0.44) | RPS6KA5CYP2D6CCR5CYP11B2CYP11B1 | |
| SCHEMBL16083674 | 0.75 | RPS6KA5 (0.52) | RPS6KA5CYP2D6CCR5CYP11B2CYP11B1 | |
| SCHEMBL927948 | 0.75 | CYP1A2 (0.64) | RPS6KA5CYP2D6CYP11B2ATMCYP3A4 | |
| SCHEMBL4138903 | 0.73 | CCR5 (0.58) | RPS6KA5CYP2D6CCR5L3MBTL1ALDH1A1 | |
| SCHEMBL30497300 | 0.72 | PDE4B (0.52) | OPRM1OPRD1OPRK1OGFRL1PDE4B | |
| SCHEMBL28645924 | 0.72 | RPS6KA5 (0.49) | RPS6KA5CYP2D6ATMALDH1A1CYP2C19 | |
| SCHEMBL3064217 | 0.70 | CCR5 (0.47) | RPS6KA5CYP2D6CCR5CYP11B2L3MBTL1 | |
| SCHEMBL3064218 | 0.70 | CCR5 (0.47) | RPS6KA5CYP2D6CCR5CYP11B2L3MBTL1 | |
| SCHEMBL19851139 | 0.69 | RPS6KA5 (0.55) | RPS6KA5CYP2D6CCR5CYP11B2CYP11B1 | |
| SCHEMBL16054503 | 0.69 | RPS6KA5 (0.55) | RPS6KA5CYP2D6CCR5CYP11B2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113348170-B | Biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-113348170-A | Biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-09-03 | — | — | CN | disclosed |