Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134368 | 0.86 | CCR5 (0.54) | CCR5CYP2D6LMNASMN1; SMN2MAPK1 | |
| SCHEMBL13743001 | 0.84 | CCR5 (0.50) | CCR5CYP2D6LMNASMN1; SMN2MAPK1 | |
| SCHEMBL13752047 | 0.83 | CCR5 (0.49) | CCR5CYP2D6LMNASMN1; SMN2MAPK1 | |
| SCHEMBL8131968 | 0.83 | CCR5 (0.67) | CCR5CYP2D6LMNA | |
| SCHEMBL4134072 | 0.80 | DYRK1A (0.53) | CCR5CYP2D6LMNASMN1; SMN2MAPK1 | |
| SCHEMBL12799041 | 0.80 | CCR5 (0.51) | CCR5CYP2D6LMNASMN1; SMN2MAPK1 | |
| SCHEMBL4126037 | 0.78 | RPS6KA5 (0.60) | CCR5CYP2D6L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7844160 | 0.78 | CCR5 (0.48) | CCR5CYP2D6LMNASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL7841863 | 0.77 | CCR5 (0.48) | CCR5CYP2D6LMNASMN1; SMN2MAPK1 | |
| SCHEMBL3064217 | 0.77 | CCR5 (0.47) | CCR5CYP2D6LMNAL3MBTL1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CXCR1 | CCR5 1/4885CYP2D6 434/4885LMNA 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.