SCHEMBL2863569

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861172	0.84	LRRK2 (0.61)	LRRK2PIM1NTRK1MAP2K4PIM2
	SCHEMBL30864287	0.83	LRRK2 (0.60)	LRRK2PIM1NTRK1MAP2K4PIM2
	SCHEMBL2866668	0.81	ALOX15 (0.44)	MAP2K4MAPK1KDM4ESTAT3HIF1A
	SCHEMBL9986229	0.79	MAPK1 (0.58)	MAP2K4MAPK1
	SCHEMBL2866811	0.79	MAP2K4 (0.55)	LRRK2MAP2K4MAPK1
	SCHEMBL2858312	0.79	LRRK2 (0.52)	LRRK2MAP2K4MAPK1KDM4ESTAT3
	SCHEMBL2857478	0.79	MAP2K4 (0.52)	PIM1MAP2K4MAPK1KDM4ESTAT3
	SCHEMBL2861069	0.79	ALPL (0.54)	MAP2K4MAPK1KDM4ESTAT3HIF1A
	SCHEMBL2872662	0.79	MAPK1 (0.46)	LRRK2MAPK1
	SCHEMBL2857271	0.79	MAPK1 (0.46)	LRRK2MAP2K4MAPK1KDM4ESTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.