SCHEMBL2857271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2864569	0.86	MAP2K4 (0.52)	MAPK1FLT3HDAC6MAP2K4MAPK3
	SCHEMBL2858312	0.80	LRRK2 (0.52)	MAPK1KDM4ESTAT3HIF1AFLT3
	SCHEMBL2857478	0.80	MAP2K4 (0.52)	MAPK1KDM4ESTAT3HIF1AFLT3
	SCHEMBL2863569	0.79	LRRK2 (0.56)	MAPK1KDM4ESTAT3HIF1AFLT3
	SCHEMBL2860104	0.79	PIM1 (0.53)	MAPK1KDM4ESTAT3HIF1AFLT3
	SCHEMBL5379661	0.79	MAPK1 (0.46)	MAPK1KDM4ESTAT3HIF1AFLT3
	SCHEMBL4903778	0.78	MAP2K4 (0.51)	MAPK1KDM4EMAP2K4
	SCHEMBL16502626	0.78	ALOX15 (0.53)	MAPK1KDM4EHDAC6KIF11ALOX15
	SCHEMBL2866668	0.77	ALOX15 (0.44)	MAPK1KDM4ESTAT3HIF1AFLT3
	Ethyl Acetate SCHEMBL27669812	0.76	PTGDR2 (0.45)	MAPK1KDM4EMAP2K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.