Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635981 | 0.77 | SLC22A12 (0.41) | KDM4EMAPT | |
| SCHEMBL28635972 | 0.74 | SLC22A12 (0.52) | KDM4EMAPT | |
| SCHEMBL28629173 | 0.70 | MAPT (0.44) | KDM4EALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL28625919 | 0.68 | HSD17B1 (0.46) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL5430100 | 0.65 | ESR1 (0.43) | — | |
| SCHEMBL1593722 | 0.61 | KDM4E (0.37) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL195563 | 0.59 | KMT2A (0.59) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL9303754 | 0.57 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL31657717 | 0.57 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL17694444 | 0.57 | THRB (0.42) | KDM4EALDH1A1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661738-B | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112661738-A | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2021-04-16 | — | — | CN | disclosed |