Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.41 |
| ▸ | SLC2A9 | Q9NRM0 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5430100 | 0.82 | ESR1 (0.43) | SLC22A12SLC2A9XDHESR1ESR2 | |
| SCHEMBL28635976 | 0.77 | KDM4E (0.32) | KDM4EMAPT | |
| SCHEMBL28635979 | 0.71 | SLC22A12 (0.76) | SLC22A12SLC2A9XDHESR1ESR2 | |
| SCHEMBL3368570 | 0.69 | ESR1 (0.59) | SLC22A12SLC2A9XDHESR1ESR2 | |
| SCHEMBL4951187 | 0.69 | POLB (0.42) | XDHABCG2KDM4EPOLBALPI | |
| SCHEMBL1071070 | 0.68 | ESR2 (0.51) | ESR1ESR2AKR1B1MAOAKDM4E | |
| SCHEMBL4525666 | 0.66 | SRD5A1 (0.43) | XDHSRD5A1ESR1ESR2AKR1B1 | |
| SCHEMBL2283832 | 0.66 | CYP3A4 (0.49) | ESR1ESR2AKR1B1MAOAKDM4E | |
| SCHEMBL4758125 | 0.65 | ESR2 (0.39) | XDHESR1ESR2AKR1B1KDM4E | |
| SCHEMBL3696621 | 0.64 | KDM4E (0.54) | ESR1ESR2KDM4EMEN1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661738-B | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112661738-A | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2021-04-16 | — | — | CN | disclosed |