SCHEMBL2863610

SCHEMBL2863610

CCC1=C(CC)c2ccccc2[CH]1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.34
FGFR2 P21802 1/20 0.34
FGFR4 P22455 1/20 0.34
FGFR3 P22607 1/20 0.34
SETD7 Q8WTS6 1/20 0.33
TP53 P04637 2/20 0.32
LMNA P02545 4/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2D6 P10635 2/20 0.31
ALOX15 P16050 2/20 0.31
RET P07949 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
TSHR P16473 1/20 0.31
ADRA2C P18825 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218144 0.78 MAP2K7 (0.33) SETD7TP53LMNACYP1A2CYP2D6
SCHEMBL1674739 0.78 FGFR1 (0.38) FGFR1FGFR2FGFR4FGFR3SETD7
SCHEMBL5689647 0.76 PDCD1 (0.35) TP53ALDH1A1MAPK1RAB9ASMN1; SMN2
SCHEMBL2872380 0.75 SETD7 (0.31) SETD7DRD3
SCHEMBL6240155 0.74 SETD7 (0.30) SETD7
SCHEMBL28025480 0.74 TP53 (0.38) FGFR1FGFR2FGFR4FGFR3SETD7
SCHEMBL6912951 0.74 NPC1 (0.32) SETD7LMNAALDH1A1MAPTNPC1
SCHEMBL217176 0.74 ALDH1A1 (0.34) FGFR1FGFR2FGFR4FGFR3SETD7
SCHEMBL5691392 0.73 KDM4E (0.35) ALOX15TSHRHTR2CALDH1A1L3MBTL1
SCHEMBL2871080 0.72 NR1H2 (0.34) SETD7CYP1A2TSHRL3MBTL1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363955-B1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORP (KR) 2008-04-09 EP claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-6943225-B2 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2005-09-13 US claimed
US-20040072677-A1 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2004-04-15 US claimed
EP-1363955-A1 MULTINUCLEAR METALLOCENE CATALYST Honam Petrochemical Corporation (KR) 2003-11-26 EP claimed
WO-2002060964-A1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORPORATION (KR) 2002-08-08 WO claimed
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed
WO-2004076502-A1 SUPPORTED MULTINUCLEAR METALLOCENE CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PREPARING THE SAME HONAM PETROCHEMICAL CORPORATION (KR) 2004-09-10 WO disclosed
US-20040072677-A1 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2004-04-15 US disclosed
WO-2003106470-A1 TRANSITION METAL COMPOUNDS THEIR PREPARATION AND THEIR USE IN CATALYST SYSTEMS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-12-24 WO disclosed
EP-1363955-A1 MULTINUCLEAR METALLOCENE CATALYST Honam Petrochemical Corporation (KR) 2003-11-26 EP disclosed
WO-2002060964-A1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORPORATION (KR) 2002-08-08 WO disclosed
US-6420507-B1 COORDINATION CATALYSTS FOR POLYMERS THE DOW CHEMICAL COMPANY 2002-07-16 US disclosed