SCHEMBL1674739

SCHEMBL1674739

CCC1=C(C)[CH]c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.38
FGFR2 P21802 1/20 0.38
FGFR4 P22455 1/20 0.38
FGFR3 P22607 1/20 0.38
ALDH1A1 P00352 4/20 0.34
LMNA P02545 4/20 0.34
HPGD P15428 4/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
PKM P14618 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALOX15 P16050 2/20 0.34
ACHE P22303 2/20 0.34
BCHE P06276 1/20 0.34
POLB P06746 1/20 0.34
PTPRC P08575 1/20 0.34
THRB P10828 1/20 0.34
IDO1 P14902 1/20 0.34
PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4622303 0.84 MEN1 (0.35) ALDH1A1LMNAHPGDMAPTMEN1
SCHEMBL5078338 0.84 MEN1 (0.35) ALDH1A1LMNAHPGDMAPTMEN1
SCHEMBL7105371 0.81 HTR1A (0.33) ALDH1A1LMNAHPGDMAPTMEN1
SCHEMBL2863610 0.78 FGFR1 (0.34) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL5690207 0.76 PDCD1 (0.39) FGFR1FGFR2FGFR4FGFR3MAPT
SCHEMBL2973349 0.75 MEN1 (0.33) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL6235802 0.74
SCHEMBL217176 0.74 ALDH1A1 (0.34) FGFR1FGFR2FGFR4FGFR3ALDH1A1
SCHEMBL5689656 0.73 KDM4E (0.38) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL2959044 0.72 P2RX7 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1377613-B1 METHOD OF MAKING INTERPOLYMERS AND PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-19 EP disclosed
EP-1412398-B1 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-24 EP disclosed
CN-101143908-B Olefin polymer DOW GLOBAL TECHNOLOGIES INC. (US) 2011-12-14 CN disclosed
US-RE43004-E1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-12-06 US disclosed
US-7999039-B2 Catalytic polymerization of olefinic monomers in the presence of a high molecular weight catalyst and a low molecular weight catalyst in a polymerization reactor system; high melt strength DOW GLOBAL TECHNOLOGIES LLC (US) 2011-08-16 US disclosed
US-RE42276-E1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC (US) 2011-04-05 US disclosed
CN-100519588-C Method of making polymer and polymer composition DOW GLOBAL TECHNOLOGIES INC (US) 2009-07-29 CN disclosed
CN-101143908-A Olefin polymer DOW GLOBAL TECHNOLOGIES INC (US) 2008-03-19 CN disclosed
US-7300983-B2 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES INC. (US) 2007-11-27 US disclosed
US-7271221-B2 Method of making interpolymers and products made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2007-09-18 US disclosed
CN-1258303-A Olefin polymers prepared with substituted indenyl containing metal complexes DOW CHEMICAL CO (US) 2000-06-28 CN disclosed
EP-0977787-A1 OLEFIN POLYMERS PREPARED WITH SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2000-02-09 EP disclosed
US-6015868-A CATALYSIS OF HIGH TEMPERATURE, SOLUTION POLYMERIZATION WHICH YIELDS HIGH MOLECULAR WEIGHT OLEFIN POLYMERS, BY USING COORDINATION CATALYST MIXED WITH AN ACTIVATING COCATALYST, EFFICIENCY THE DOW CHEMICAL COMPANY (US) 2000-01-18 US disclosed
CN-1223670-A elastomer and preparation method thereof DOW CHEMICAL CO (US) 1999-07-21 CN disclosed
EP-0910593-A1 ELASTOMERS AND PROCESS FOR THEIR MANUFACTURE THE DOW CHEMICAL COMPANY (US) 1999-04-28 EP disclosed
CN-1200735-A Substituted indenyl contg. metal complexes and olefin polymerization process DOW CHEMICAL CO (US) 1998-12-02 CN disclosed
WO-1998049211-A1 OLEFIN POLYMERS PREPARED WITH SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1998-11-05 WO disclosed
EP-0874860-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1998-11-04 EP disclosed
WO-1998002471-A1 ELASTOMERS AND PROCESS FOR THEIR MANUFACTURE THE DOW CHEMICAL COMPANY (US) 1998-01-22 WO disclosed
WO-1997015583-A1 SUBSTITUTED INDENYL CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1997-05-01 WO disclosed